HA was first isolated in 1934 from bovine tissue researchers Karl Meyer and John Palmer, and large-scale production began in the 1970s extracting such polymer from rooster combs. However, growing demand for cruelty-free and vegan products has led to most of HA being made with bio-fermentation-based processes.

Fermented Hyaluronans come from bacterial cultures, privileging those which produce HA in reasonably large amounts, usually strains of streptococci, such as Streptococcus equi ssp. zooepidemicus. This mechanism happens since bacteria naturally coat themselves with HA to help elude host immune systems and since bacteria’s HA production is an ongoing process, we are able to extract the polymer without damaging the culture.

Furthermore, not only bio-fermented hyaluronic acid is much more sustainable and less cruel than its avian counterpart, but it also comes with a reduced risk of biological contamination than the traditional animal-derived or chemically-synthesised ones.

As stakeholders in the Health & Wellness Community, at Sino LifeSciences we embrace this green new normal, sourcing our SinoHyal line directly from our trusted partners all over the world which adopt the most modern and sustainable manufacturing technologies.